99% Estrogen Hormone Estradiol for Anti Cancer Estradiol /Estradiol Benzoate

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Estradiol Benzoate
CAS: 50-50-0
Synonym: 17β-Estradiol 3-Benzoate
Application: A steroid used for biological research purposes
Purity: 99%
Molecular Weight: 376.49
Molecular Formula: C25H28O3
Packing:Foil bag
Standards:USP27
Manufacturer:HKSJG

Detailed Descriptions with Estradiol:
Estradiol
CAS: 50-28-2
Molecular Formula: C18H24O2
Molecular Weight: 272.38
Content: 99%
Properties: White crystalline powder
Packing: 1KG/bag
 estradiol C18H24O2 being a sex hormone. With alpha, beta, two types of alpha 
physiological function is strong. Steiner, winter (Wintersteiner et al. 1935) was 
extracted from the horse urine pregnancy, moreover also can cause from the urine, 
placenta, pig ovary, etc. There is also a male horse testis or urine. Because it has the 
very strong sex role, so that it or its ester is, in fact, ovarian secretion of the sex 
hormones of the most important. Estradiol benzoate is decided to one of the international 
unit of sex hormone titer standard substance and used.

Function and use: It is a kind of estrogen, can promote and regulate the normal 
development of womens genitals and secondary. Can cause hyperplasia of mammary gland 
carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and 
reduce the secretion of milk. Potent mammalian estrogenic hormone produced by the ovary.

Application:
 Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the 
primary female sex hormone. It is named for and is important in the regulation of the 
estrous and menstrual female reproductive cycles. Estradiol is essential for the 
development and maintenance of female reproductive tissues but it also has important 
effects in many other tissues including bone. While estrogen levels in men are lower 
compared to women, estrogens have essential functions in men as well. Estradiol is found 
in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Know more about Estradiol:
 Estrogens direct the development of the female genotype in embryogenesis and at puberty. 
Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is 
an estradiol analog which contains a benzyl ester at the C-3 position and is often used in 
combination with a progestin to induce estrus in domestic livestock. This compound binds 
to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in 
the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to 
estradiol.

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Do NOT use hydrocortisone acetate suppositories if:
1.you are allergic to any ingredient in hydrocortisone acetate suppositories
2.you are taking mifepristone
3.you have a rectal obstruction, abscess, or perforation; irritation of the peritoneum 
(lining of the abdomen); or fistulas
Contact your doctor or health care provider right away if any of these apply to you.
Before using hydrocortisone acetate suppositories:
Some medical conditions may interact with hydrocortisone acetate suppositories. Tell your 
doctor or pharmacist if you have any medical conditions, especially if any of the 
following apply to you:
1.if you are pregnant, planning to become pregnant, or are breast-feeding
2.if you are taking any prescription or nonprescription medicine, herbal preparation, or 
dietary supplement
3.if you have allergies to medicines, foods, or other substances
4.if you have a parasitic, bacterial, fungal, or viral infection; diabetes; diarrhea; 
swelling of the esophagus; stomach problems; blockage or the intestine or other intestinal 
problems;
measles; tuberculosis (TB); a positive TB skin test; chicken pox; shingles; herpes 
infection of the eye; ulcers; kidney problems; high blood pressure; thyroid problems; or 
you have received a recent vaccination
5.if you have a history of heart failure or heart attack.

Some MEDICINES MAY INTERACT with hydrocortisone acetate suppositories. Tell your health 
care provider if you are taking any other medicines, especially any of the following:

1.Barbiturates, carbamazepine, cholestyramine, colestipol, fluconazole, hydantoins eg, 
phenytoin, lithium, rifampin, or thioamines (eg, propylthiouracil) because they may 
decrease hydrocortisone acetate suppositoriess effectiveness
2.Aprepitant, clarithromycin, estrogens (eg, estradiol), macrolide immunosuppressants (eg, 
tacrolimus), nefazodone, or steroidal contraceptives (eg, birth control pills) because 
side effects such as adrenal gland or central nervous system problems may occur
3.Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), live vaccines, 
macrolide immunosuppressants (eg, tacrolimus), nondepolarizing muscle relaxants (eg, 
vecuronium), ritodrine, or theophylline because their actions and the risk of their side 
effects may be increased by hydrocortisone acetate suppositories
4.Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), interleukin-2, 
mifepristone, or nondepolarizing muscle relaxants (eg, vecuronium) because their 
effectiveness may be decreased by hydrocortisone acetate suppositories
This may not be a complete list of all interactions that may occur. Ask your health care 
provider if hydrocortisone acetate suppositories may interact with other medicines that 
you take. Check with your health care provider before you start, stop, or change the dose 
of any medicine.
Applications:
1. Mainly used for the treatment of rheumatoid arthritis, rheumatic fever, gout, bronchial 
asthma.
2. Injection for tuberculosis or purulent meningitis, tuberculous pleurisy, empyema, 
arthritis, tenosynovitis, tendon strain, sprain, nodular prurigo, lichen planus, etc.
3. Eye drops for a variety of ophthalmia.
4. Cream for atopic or seborrheic dermatitis, pruritus.
Attention:
Long-term large dose of corticosteroid hormone drugs, which can cause iatrogenic adrenal 
hyperactivity disorder, manifested as moon face, central obesity, thin skin and purple 
stripes, muscle weakness and atrophy, osteoporosis.
Important safety information:
1.If your symptoms do not get better within 7 days or if they get worse, check with your 
doctor.
2.Do not use hydrocortisone acetate suppositories for other rectal conditions at a later 
time.
3.Do not get hydrocortisone acetate suppositories in your eyes. If you get hydrocortisone 
acetate suppositories your eyes, immediately flush them with cool tap water.
4.Check with your doctor or pharmacist concerning the use of a stool softener or bulk 
laxative to help improve your symptoms.
5.Check with your doctor before having vaccinations while you are using hydrocortisone 
acetate suppositories.
6.Hydrocortisone acetate suppositories may lower the ability of your body to fight 
infection. Avoid contact with people who have colds or infections. Tell your doctor if you 
notice signs of infection like fever, sore throat, rash, or chills.
7.Hydrocortisone acetate suppositories should be used with extreme caution in CHILDREN; 
safety and effectiveness in children have not been confirmed.
8.PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need 
to discuss the benefits and risks of using hydrocortisone acetate suppositories while you 
are pregnant. It is not known if this medicine is found in breast milk. If you are or will 
be breast-feeding while you use hydrocortisone acetate suppositories, check with your 
doctor. Discuss any possible risks to your baby.

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